Mistress and Master Functional Fragrance is best applied directly under your nose to maximize the impact on yourVNO function. Those brands that suggest you use a spray or place the fragrance on your pulse points (neck, wrist, behind ears), are in fact doing a disservice to what pheromones are all about. When a spray is used, if there is any true human derived pheromone in the formulation, it is dispersed in the air, with a minimal amount entering the nasal cavity. Three strokes under the nose is all you will need for maximum benefit and the results should last for up to three hours. Using too much may cause tingling in the extremities and light headedness.

Enjoy!

HM