Phero\'s aren\'t alive. Natural or synthetic. They are organic molecules, not living cells. They can\'t be \"killed.\" In general, the difference between natural and synthetic preparations is the composition of impurities. The things that \"accompany\" natural production and isolation of _lots_ of things - perfumes, flavorings - are usually different from the things that accompany synthetic production of the same compounds. It\'s definately possible that alcohol could _affect_ natural pheros differently than synthetic - because of soluability differences of the impurities of the natural vs the synthetic preparations. But the sites that warn of alcohol _killing_ pheros are just spewing hype...

The article that referred to pheros in alcohol smelling bad has already been discussed in this forum. It was a flawed experimental design. Phero\'s plus alcohol were placed under a subject\'s nose. That doesn\'t happen in practice, unless you\'re having your target sniff it out of the bottle - the alcohol normally evaporates.

Considering the subtleness of perfume drydown, it wouldn\'t surprise me if phero\'s in alcohol behaved very differently over time than the same phero\'s in oil / di-glycols. Especially in the presence of complex masking perfumes. But that\'s a very different topic than that of alcohol \"destroying\" the pheros.