Kaminski
RM, Marini H, Won-Joo K, and Rogawski MA (2005) Anticonvulsant activity of androsterone and etiocholanolone.
Epilepsia 46:819–827.
"Androstanediol is a positive modulator of
GABAA receptors (Frye et al., 1996) with
potent anxiolytic
and anticonvulsant activity (Frye and Reed, 1998; Reddy,
2004a,b); recently, we confirmed that
androsterone has similar
systemic activities (Kaminski et al., 2005)."
An anxiolytic is any drug or therapy
used in the treatment of anxiety disorders. I am following up on this recent report to determine whether GABA
interaction might be the means by which androsterone (as used in SoE for men) might indicate reduced anxiety in the
wearer as well as reduce anxiety in people (especially women) who are exposed to it.
It's somewhat satisfying
to see the Forum members indicate this effect, but more satisfying to find scientific support for the effect.
JVK
Discussion on this topic can be found by
clicking
here.
Last edited by oscar; 04-20-2006 at 02:40 PM. Reason: Inserting Link
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