I alternate 'mone types every
few days or weeks depending on my mood and/or purpose, and haven't experienced problems or radical changes in
reactions. Maybe your persona and/or perception changes. O course I don't use AE. I mainly stick to some combo of
SOE, NPA, TE, A-1, IMPI and CS 'rone. I have Chikara, Perception and EW but rarely use them.
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