Close

Results 1 to 16 of 16
  1. #1
    Sadhu bjf's Avatar
    Join Date
    Jan 2003
    Posts
    3,781
    Rep Power
    7297

  2. #2
    zeta male metropolitan's Avatar
    Join Date
    Apr 2005
    Location
    new york city
    Posts
    201
    Rep Power
    6086

    Default

    would love to read this

    article but the html page is no longer active. did anyone by any chance download it or copy it?

    thanks

  3. #3
    Phero Pro NaughtieGirl's Avatar
    Join Date
    Mar 2005
    Location
    Way too far North!
    Posts
    974
    Rep Power
    6189

    Default

    Quote Originally Posted by metropolitan
    would

    love to read this article but the html page is no longer active. did anyone by any chance download it or copy it?



    thanks
    Hey Metro!

    When I clicked on it, I came up with this (see below) That makes me suspect your

    browser is at fault. Which one are you using?
    Intriguing link btw, that I will delve into tomorrow.

    Thanks!our Perception




    Steroid Urine Type Odorants &

    Sandalwood Type Odorants


    by John C. Leffingwell,

    Ph.D.


    Photo by permission of M. Roudintska -

    Art &

    Parfum


    Cyclic

    Terpenoid Odorants


    Bicyclic Terpenoid

    Odorants


    Acyclic

    Terpenoid

    Odorants


    Ionones,

    Irones, Damascones & Structurally Related

    Odorants


    Acyclics

    (Alcohols, Esters, Acids,

    Aldehydes)


    Lactones



    Sesquiterpenoi

    d Related

    Odorants


    Steroi

    d Urine Type Odorants


    Sandalwood Type

    Odorants


    Musk

    Odorants


    Miscellaneous



    Enantiomer & Odor Description Odour Threshold

    (PPB)


    Steroid Type

    Odorants


    .

    (+)-androstenone

    - strong urine

    odor


    0.18

    (-)-andros

    tenone
    -

    odorless


    Odorless

    [color=#0000ff

    ](-)-androsta-4,16-dien-3-one[/color] -

    odorless


    Odorless

    [color=#0000ff

    ](+)-androsta-4,16-dien-3-one[/color] - very persistent odor of urine &

    sweat


    0.98

    (+)-5-alph

    a-androst-16-en-3-alpha-ol
    - Animalic, musk-like odor with a strong (fine) sandalwood

    tonality

    0.02

    ent-(-)-5-alpha-andro

    st-16-en-3-alpha-ol
    - Weaker with a detection threshold level about six orders of magnitude higher

    than 5-alpha-androst-16-en-3-alpha-ol

    NA

    Nature Identical Sandalwood

    Odorants




    (-)-(1'S,2'R,4'R)-

    (Z)-beta-santalol
    - Typical sandalwood scent, identical to the natural

    product.

    NA

    (+)-(1'R,2'S,4'S)-(Z)-b

    eta-santalol
    - No scent

    (odorless).

    Odorless

    (-)-(1'S,2'R,4R)- (E)-beta-santalol - Scent similar to (-)-(1'S,2'R,4'R)-(Z)-beta-santalol but less

    intense.

    NA

    (+)-(1'R,2'S,4'S)-

    (E)-beta-santalol
    - No scent (odorless).

    Odorless

    Sandalwood Type Odorants from

    Campholenic aldehyde






    (-)-(1'R)-4-(2',2',3'-trimethyl-

    3'-cyclopenten-1'-yl)-4-penten-1-al
    - fragrance further possessing an aldehydic note,

    reminiscent of citronellal, citrusy, spicy, recalling the odor of the citronella leaves. As to its bottom note, it

    has a character which is reminiscent of the odor of 3-(4-tert-butyl-1-phenyl)-2-methylpropanal, but with an even

    greener connotation and a slightly orangy

    aspect


    NA

    (+)-(1'S)

    -4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-1-al
    - a more metallic and

    aldehydic odor, recalling that of trans-4-decenal, and the bottom note of which is more floral and even stronger in

    the aqueous character. The use of this latter compound to enhance the latter odor character in perfumed compositions

    and articles is in fact preferred to that of its

    (-)-(1'R)-enantiomer


    NA

    [color=#00

    00ff](-)-(1'R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-pentenenitrile[/color] -

    a woody-citrus, fruity and slightly fatty odor prefered to the

    (+)-(1'S)-isomer


    NA

    [color=#0000ff

    ](+)-(1'S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-pentenenitrile[/color] - not

    as prefered an odor as the

    (-)-(1'R)-isomer


    NA

    [color=#0000ff

    ](-)-(1'R,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-pentenenitrile[/color] -

    citrus, fruity and fresh character accompanied by a sandalwood bottom

    character


    NA

    (+)-(1S,2s)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-pentenenitrile - odor not

    described other than to say the (1'R)-isomers are

    preferred


    (-)-(1'R,2S)

    -2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-pentenenitrile
    - a sandalwood

    odor wherein the desired fruity-citrus character of the (-)-(1'R,2R)-isomer is no longer

    present


    NA

    (+)-(1'S

    ,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-pentenenitrile
    - odor not

    described other than to say the (1'R)-isomers are

    preferred


    (-)-(1'R,2R)

    -2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-penten-1-ol - elegant and powerful sandalwood note

    (prefered of the four

    isomers)


    NA

    (+)-(1'

    S,2S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-penten-1-ol
    - odor is less

    rich in the precious "lait de santal" type odor character present in the (-)-(1'R,2R)- and (-)-(1'R,2S)-

    isomers


    NA

    (-)-(1'R

    ,2S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-penten-1-ol
    - sandalwood

    note is not as powerful as the (-)-(1'R,2R)-isomer but is accompanied of a more marked woody-cedar

    character


    NA

    (+)-(1S,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-penten-1-ol - odor is

    less rich in the precious "lait de santal" type odor character present in the (-)-(1'R,2R)- and (-)-(1'R,2S)-

    isomers


    NA

    (-)-(1'R

    ,E)-3,3-dimethyl-5-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-2-ol
    - develops a

    sandalwood note, the character of which is strongly reminiscent of the typical milky odor of

    sandalwood


    NA

    (+)-(1

    'S,E)-3,3-dimethyl-5-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-2-ol -
    drier,

    more woody-cedar and less milky than that of its (-)-(1'R,E)-

    isomer


    NA

    (+)-(1'S,

    2S,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
    - develops a

    sandalwood note of remarkable strength, wherein the typical milky character is represented at its best and

    accompanied by a slightly animal note; prefered of four possible

    isomers


    NA

    (-)-(1'R

    ,2R,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
    - weakest and less

    characteristic sandalwood note than any of the other

    isomers


    NA

    (+)-(1'S

    ,2R,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
    - ranked in 3d place

    of 4 isomers for its sandalwood

    odor


    NA

    (-)-(1'R,2S

    ,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
    - weaker and less

    characteristic sandalwood note than the (+)-(1'S,2S,E)-isomer but superior to the (+)-(1'S,2R,E)- or

    (-)-(1'R,2R,E)-

    isomers


    NA

    (1'R,E)-

    (+)-2-Methyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
    - fresh and strong

    sandalwood oil odor associated with green

    trees


    51

    (1'S,E)-(-

    )-2-Methyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
    - dry and weak sandalwood

    oil odor with a milky and floral

    note


    424

    (1'R,E)-(-

    )-2-Ethyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
    - clean, bright and strong

    sandalwood oil odor with richness and a woody

    note


    0.85

    (1'S,E)-(

    -)-2-Ethyl-4-(2,2,3-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
    - milky sandalwood oil odor

    with a cedar

    character


    44

    (-)-(1R)-2-methyl-4-(2',2',3'- trimethyl-3'-cyclopenten-1'-yl) -4-penten-1-al - possesses an

    unexpected odor in view of the prior knowledge regarding the odor properties of campholenic aldehyde derivatives. It

    develops a woody-sandalwood type odor note, slightly aldehydic, which is more reminiscent of the cedar-pine odor

    connotation than of the sandalwood type one, which note is combined with a distinct marine, ozone character. The

    latter is reinforced in the bottom note, which is strongly ozone-marine-like, recalling the odor of seaweeds. In

    addition, the odor of this compound has a good strength and

    tenacity.


    NA

    (+)-(1S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl) -4-penten-1-al - woody,

    sandalwood, aldehydic, faintly

    aqueous


    NA



    (1'S,1''S,2'S,3''R,5''R)-Javanol
    - sandalwood, creamy, warm,

    strong


    NA

    (1'R,1''R,2R,3''S,5''S)-Javanol - lactonic, lily of the

    valley


    NA

    (1'R,1''S,2R,3''R,5''R)-Javanol - lactonic, with a sandalwood

    aspect


    NA

    (1'S,1''R,2S,3''S,5''S)-Javanol - floral, rosy, milky,

    sandalwood


    NA

    (-)-(1

    S,E)-5-(2',2-dimethyl-3'-methylene-1'-cyclohexyl)-3,3-dimethyl-4-penten-2-ol
    - Woody, sandal, sweet

    note, reminiscent of the odor of the bark and milk of the sandalwood

    tree.

    NA

    (+)-(1'R,E)-5-(2',2-dim

    ethyl-3'-methylene-1'-cyclohexyl)-3,3-dimethyl-4-penten-2-ol
    - Sandalwood odor, but distinctly

    different than the (-)-(1S,E)-isomers

    NA





    Other Sandalwood

    Odorants




    (1R,3R

    ,1'S,2'R,4'S,6'S)-(+)-threo-trans-3-isocamphylcyclohexanol
    - Strong, diffusive, and

    sandalwood-like odor; natural sandalwood odor, but very strong and

    keen

    0.2

    (1S,3S,1'R,2S,4'R,6'R)-(-)-threo-trans-3-isocamphylcyclohexanol - weak, moldy and woody

    odor

    200

    (1S,3S,1'S,2R,4'S,6'S) (+)-erythro-trans-3-isocamphylcyclohexanol - sandalwood like odor without moldy feeling,

    and it is sufficiently

    diffusive

    7

    (1R,3R,1'R

    ,2'S,4'R,6'R)-(-)-erythro-trans-3-isocamphylcyclohexanol
    - strong, warm sandalwood

    odor

    3

    (+)-(1S,3R,6

    R,8R)-8-tertbutylbicyclo[4.4.0]decan-3-ol
    - strong, sandalwood like, warm, sweet and fatty, long

    persisting,

    NA

    (-)-

    (1R,3S,6S,8S)-8-tertbutylbicyclo[4.4.0]decan-3-ol
    - very weak, fatty, hardly perceptible, remote

    reminiscent to animal

    notes.

    NA

    (2S,3R,4E)-3-m

    ethyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - very strong, sandal(wood),

    animalic

    5

    (2R,3S,4E)-3-

    methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - weak,

    woody

    168

    (2R,3S,4E)-3-m

    ethyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - sandal(wood),

    animalic

    70

    (2S,3R,4E)-3

    -methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    -

    woody

    72

    (2R,3R,4E)-3-me

    thyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - sandal(wood),

    floral

    137

    (2S,3S,4E)-3-

    methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - very weak

    floral

    159

    (2S,3S,4E)-3-

    methyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - strong sandal(wood),

    floral

    46

    (2R,3R,4E)-3-m

    ethyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
    - weak

    floral

    204

    (1R,2'R,3'S)-Ebanol

    - weak, no sandalwood odor relevance

    >100 (relative in

    series)

    (1S,2'S,3'R)-Ebanol

    - Powerful sandalwood, more than 100X more powerful than its enantiomer (based on relative GC sniff threshold) and

    more than 3X stronger than (1R,2'S,3'R)-Ebanol

    1 (relative in

    series)

    (1R,2'S,3'S)-Ebanol

    - Slight sandalwood relevance, both enantiomers weak

    >100 (relative in

    series)

    (1S,2'R,3'R)-Ebanol

    - No sandalwood relevance, both enantiomers weak

    >100 (relative in

    series)

    (1R,2'S,3'R)-Ebanol

    - Powerful sandalwood, more than 33X more powerful than its enantiomer and more than 3X weaker than

    (1S,2'S,3'R)-Ebanol

    3 (relative in

    series)

    (1S,2'R,3'S)-Ebanol

    - no sandalwood relevance

    >100 (relative in

    series)

    (1R,2'R,3'R)-Ebanol

    - no sandalwood relevance

    >100 (relative in

    series)

    (1S,2'S,3'S)-Ebanol

    - no sandalwood relevance

    >100 (relative in

    series)

    HOME

    [color=#

    ffffff]Copyright 2002 - Leffingwell & Associates[/color]
    Treasure Every Moment that you have
    Yesterday is History - Tomorrow is a Mystery
    Today is a Gift - That's why It's called the Present!
    (Unknown source)

  4. #4
    zeta male metropolitan's Avatar
    Join Date
    Apr 2005
    Location
    new york city
    Posts
    201
    Rep Power
    6086

    Default

    when i try the link now it

    works, so maybe the site was down.
    thanks for posting the info. been playing with essential oils and fragrance

    oils and sandalwood is a great one.
    i recommend checking out the body shop perfume oils.

  5. #5
    Phero Pro NaughtieGirl's Avatar
    Join Date
    Mar 2005
    Location
    Way too far North!
    Posts
    974
    Rep Power
    6189

    Default

    Quote Originally Posted by metropolitan
    when i

    try the link now it works, so maybe the site was down.
    thanks for posting the info. been playing with essential

    oils and fragrance oils and sandalwood is a great one.
    i recommend checking out the body shop perfume oils.

    I agree, essential oils and aromatherapy seem to be the perfect complement to pheromones. Some of the nicer EO's

    are quite pricey though. Sandalwood is one of the nice ones I did splurge on. There is tons of good info on this

    forum about EO's as well. You can access it with the search function.
    Treasure Every Moment that you have
    Yesterday is History - Tomorrow is a Mystery
    Today is a Gift - That's why It's called the Present!
    (Unknown source)

  6. #6
    Phero Guru Rbt's Avatar
    Join Date
    Feb 2005
    Location
    Midwest US
    Posts
    1,579
    Rep Power
    6310

    Default

    Quote Originally Posted by metropolitan
    when i try the

    link now it works, so maybe the site was down.
    thanks for posting the info. been playing with essential oils and

    fragrance oils and sandalwood is a great one.
    i recommend checking out the body shop perfume oils.

    Browsers and the internet itself can get finicky. Often when I get an "unable to find" or other failure, if I come

    back a while later all is fine. Although sometimes things *do* seem to screw up the browser software and I find it

    best to shut it down and start anew (sometimes just the browser, othertimes I turn off the whole system and reboot.

    Only way to totally clear out any junk in the RAM memory.)

  7. #7
    Phero Pharaoh BassMan's Avatar
    Join Date
    May 2002
    Location
    Orlando, FL
    Posts
    1,234
    Rep Power
    7283

    Default

    Quote Originally Posted by bjf
    These are what are known as

    opto-isomers. Identical except one is a mirror image of the other. There are many such compounds in nature. The ones

    with the "wrong" mirror image don't fit into the proper receptor sites in the body and are therefore usually not

    biologically active.

    In other words, there is an odorless none, but it is not a pheromone.

    Bass
    somewhere between amused and obsessed...

  8. #8
    Phero Pro NaughtieGirl's Avatar
    Join Date
    Mar 2005
    Location
    Way too far North!
    Posts
    974
    Rep Power
    6189

    Default

    Quote Originally Posted by metropolitan
    when i

    try the link now it works, so maybe the site was down.
    thanks for posting the info. been playing with essential

    oils and fragrance oils and sandalwood is a great one.
    i recommend checking out the body shop perfume oils.

    Me too! If you're new at it I can recommend Mindy Green's "Natural Perfumes" I just bought it from Amazon.com.

    It even has a paragraph or two about pheromones in the introduction.

    Contents go a bit like this:
    - basics of

    aromatherapy
    - blending fundamentals,
    - a review of 40 oils
    - 2 beginning blending lessons
    - 30 fragrance

    recipes
    - elemental blends
    - resource directory

    What I like about it is that she suggests blends and then

    tells you which particular oil to vary in quantity to make it suit your own taste. Proportions for fragrance

    products. EO note type and odor intensity.

    But I'm really new at it. You might already know all that stuff.



    BassMan: Thanks for the info. Learned something new today! I was somewhat mystified by that link.
    Treasure Every Moment that you have
    Yesterday is History - Tomorrow is a Mystery
    Today is a Gift - That's why It's called the Present!
    (Unknown source)

  9. #9
    Doctor of Scentology DrSmellThis's Avatar
    Join Date
    Jun 2002
    Location
    Oregon
    Posts
    6,233
    Rep Power
    7781

    Default

    Quote Originally Posted by BassMan
    These are what

    are known as opto-isomers. Identical except one is a mirror image of the other. There are many such compounds in

    nature. The ones with the "wrong" mirror image don't fit into the proper receptor sites in the body and are

    therefore usually not biologically active.

    In other words, there is an odorless none, but it is not a

    pheromone.

    Bass
    You mean there's a good chance it's not, don't you? Can we be certain?
    DrSmellThis (creator of P H E R O S)

  10. #10
    zeta male metropolitan's Avatar
    Join Date
    Apr 2005
    Location
    new york city
    Posts
    201
    Rep Power
    6086

    Default

    yeah, i also have the mindy

    green book!
    another good book is

    Per

    fumes, Splashes & Colognes : Discovering and Crafting Your Personal Fragrances

    by



    Nancy M. Booth

    a lot of informatioin on perfumery, essential oils, categories of scents and a lot more.

    worth buying if you're into personal perfumery.

    i also recently got

    Sce

    nts & Scentuality: Essential Oils & Aromatherapy for Romance, Love, and Sex (Paperback)

    by



    Valerie Ann Worwood

    and this is an excellent aromatherapy for love, sex and romance. a tons of formulas and

    recipes and what the intended results are for. it uses different angle. less concerned with perfumery and more with

    the emotional, psychological, and sensual reactions we have to certain essential oils. very very good.

  11. #11
    Phero Pro NaughtieGirl's Avatar
    Join Date
    Mar 2005
    Location
    Way too far North!
    Posts
    974
    Rep Power
    6189

    Default

    Quote Originally Posted by metropolitan
    yeah, i

    also have the mindy green book!
    another good book is

    Per

    fumes, Splashes & Colognes : Discovering and Crafting Your Personal Fragrances

    by



    Nancy M. Booth

    a lot of informatioin on perfumery, essential oils, categories of scents and a lot more. worth

    buying if you're into personal perfumery.

    i also recently got

    Sce

    nts & Scentuality: Essential Oils & Aromatherapy for Romance, Love, and Sex (Paperback)

    by



    Valerie Ann Worwood

    and this is an excellent aromatherapy for love, sex and romance. a tons of formulas and

    recipes and what the intended results are for. it uses different angle. less concerned with perfumery and more with

    the emotional, psychological, and sensual reactions we have to certain essential oils. very very good.
    Hey

    thanks! I already bought Nancy Booth's book along with Mindy Green's but I haven't read it yet. I

    spent the evening last night highlighting in Mindy Green's book. V.A. Worwood's book is definitely next on my

    list. I just love the "learning curve" of new endeavors!
    Treasure Every Moment that you have
    Yesterday is History - Tomorrow is a Mystery
    Today is a Gift - That's why It's called the Present!
    (Unknown source)

  12. #12
    Phero Enthusiast countesszero's Avatar
    Join Date
    Nov 2004
    Location
    Maryland
    Posts
    274
    Rep Power
    6285

    Default

    Hi Madini.com is also a

    good site if you want EO's or essences. This is were I get my honeysuckle, violet and rose oils from. Their prices

    are reasonable too.

    The Countess

  13. #13
    zeta male metropolitan's Avatar
    Join Date
    Apr 2005
    Location
    new york city
    Posts
    201
    Rep Power
    6086

    Default

    Hi Madini.com is

    also a good site if you want EO's or essences.
    i checked them out, sounds interesting, so i just ordered

    some of their samples.

  14. #14
    Phero Pharaoh BassMan's Avatar
    Join Date
    May 2002
    Location
    Orlando, FL
    Posts
    1,234
    Rep Power
    7283

    Default

    Quote Originally Posted by DrSmellThis
    You mean

    there's a good chance it's not, don't you? Can we be certain?
    It would probably be better to state it

    as:

    If the odorless molecule _is_ a pheromone, it's probably a quite different one from the odorous one.



    For example, the drug thalidomide - it was prescribed for morning sickness, later found to cause profound birth

    defects. One isomer controlled the morning sickness, the other the birth defects.

    Another example - vitamin E.

    The D form is active in the body, the L form inactive. Which is why synthetic E (which is a mixture of the D and L

    forms) is only half as potent as natural E (which is almost all D).

    So, yeah, I probably overstated it, but

    optical rotation usually makes a very large difference in biological activity.

    -Bass
    somewhere between amused and obsessed...

  15. #15
    Doctor of Scentology DrSmellThis's Avatar
    Join Date
    Jun 2002
    Location
    Oregon
    Posts
    6,233
    Rep Power
    7781

    Default

    Thanks for the clarification.

    DrSmellThis (creator of P H E R O S)

  16. #16
    Banned User Le Sillage's Avatar
    Join Date
    Apr 2005
    Posts
    109
    Rep Power
    0

    Default

    Yeah, D and L phenylalanine have

    totally different functions, both generally positive, but very different.

    So do R and S ALA. I don't

    remember which, but one is negative, one is beneficial. Together, they sort of even out into a zero sum

    game.

    With something like androstadienone, there's a definite receptor, and we know what it is (the

    vno).

    With something like androstenol, we see a physiological change in subjects, but have no idea why it's

    occuring. It's not through the vno.

    That doesn't mean that a chiral switch of pheromones can't be tested,

    however. Everyone of us here is testing mones all the time, but there's a catch with chiral forms, and that's that

    there's barely ever enough to test...

    Chiral switches are hard to get, and most known synthesis routes are

    way too costly to be ready for even a smidge of prime time. You suffer from the fact that you don't have the

    research dollars in this industry that you do in pharmaceuticals. Even those multibillion dollar companies avoided

    chiral switches for years, due to the costs of development.

    This article says that it took 15 years

    (supposedly) to get Nexium out of Prilosec. Guh! Nexium is one half the man that Prilosec is. Lots of good info

    here:

    http://pubs.acs.org/cen/coverstory/8...18chiral2.html

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •