Putative pheromone activates cortical fields in the human brain...

[Chemo (BDC Concepts)]

The putative

pheromone androstadienone activates cortical fields in the human brain related to social cognition.

Gulyas

B, Keri S, O'Sullivan BT, Decety J, Roland PE.

Department of Neuroscience, Karolinska Institute, S-171 77

Stockholm, Sweden. balazs.gulyas@neuro.ki.se

Abstract:
Using

15O-butanol positron emission tomography (PET), we measured regional cerebral blood flow changes in five healthy

young women during exposure to androstadienone, a putative human pheromone, as well as pleasant

(gamma-methyl-ionone), unpleasant (methyl-thio-butanoate), and neutral (dipropylene glycol; vehicle compound)

odours. Compared with the odorous substances, androstadienone activated a widely distributed neuronal network. Two

large cortical fields exhibited consistent activation in each contrast: the anterior part of the inferior lateral

prefrontal cortex (PFC) and the posterior part of the superior temporal cortex (STP). Intriguingly, these areas were

deactivated by gamma-methyl-ionone and methyl-thio-butanoate. These brain regions can be identified as cortical

fields underlying other than olfactory functions, including various aspects of social cognition and

attention.

I don't know if these articles have been posted before so someone feel free to delete these if

redundant.

Looks like dienone may hold promise

Bobby

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