View Full Version : Androstenone receptor?
jvkohl
09-16-2007, 06:16 PM
http://news.yahoo.com/s/nm/20070916/sc_nm/genes_odor_dc_2;_ylt=Aqn8eVxI67iw3c7W.o_a9DIE1vAI
"There is
some evidence published showing this chemical can modify the mood or hormone levels in humans," he said. "What we
don't know is whether the receptor we found was in any way involved in this process."
Another article about
this:
http://newswire.rockefeller.edu/?page=engine&id=660
James V. Kohl
The Scent of Eros
jvkohl
09-19-2007, 11:03 PM
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17873857&ordinalpos=1&itool
=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel. Pubmed_RVDocSum
From the article:
"Recent
expression analysis shows that OR7D4 is selectively expressed in human nasal epithelium." Citation: Zhang, X. et al.
Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarray. Genome Biol.
8, R86 (2007).
Once again, there appears to be no support for the concept that human pheromones act through
what appears to be a non-existent human VNO.
James V. Kohl
The Scent of Eros
Lokua
09-19-2007, 11:21 PM
so...like what...if i have a cold
ill be immune to phero's?
BGuy20
09-21-2007, 06:59 AM
IIRC, I read that the receptor
forms differently in different people (same DNA but different end result... polymorphic or something), which they
said is why some people perceieve the smell of -None differently. I think the same article said that up to about
half of people can be "trained" to smell the scent after a while.
I've certainly noticed this happening with
me, I can notice -None much more easily than I could when I first started.
jvkohl
09-21-2007, 07:12 PM
IIRC, I read
that the receptor forms differently in different people (same DNA but different end result... polymorphic or
something), which they said is why some people perceieve the smell of -None differently. I think the same article
said that up to about half of people can be "trained" to smell the scent after a while.
I've certainly
noticed this happening with me, I can notice -None much more easily than I could when I first
started.
Theoretically, exposure induces change in receptor expression via gene activation. The
theory behind this is very difficult to grasp without some knowledge of the immune system (e.g., genetics), and its
interaction with the neuroendocrine system. So most people might better understand the reductionist approach: the
immune and olfactory systems function in similar ways to recognize what is like us, or is not like us. We can
recognize a pig's smell as being like some of us, but hopefully not you or me. I am (half jokingly) concerned that
you might be slowly learning that you may smell like a pig. But even pigs don't require a VNO to "know" one pig
from another.
James V. Kohl
The Scent of Eros
tenaciousBLADE
09-22-2007, 12:27 PM
hehe.. cute joke
there.
ummm...
I think this: "Theoretically, exposure induces change in receptor expression via gene activation."
is cool :cool::D
Animals and humans... what complex and cool beings.. :p
jvkohl
09-22-2007, 06:41 PM
hehe..
cute joke there.
Happy to learn you "got" the joke. If I can't have some fun with this stuff once in a
while, I'll quit learning about it.
James V. Kohl
The Scent of Eros
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