Androstenone receptor?

[jvkohl]

http://news.yahoo.com/s/nm/20070916/sc_nm/genes_odor_dc_2;_ylt=Aqn8eVxI67iw3c7W.o_a9DIE1vAI

"There is

some evidence published showing this chemical can modify the mood or hormone levels in humans," he said. "What we

don't know is whether the receptor we found was in any way involved in this process."

Another article about

this:
http://newswire.rockefeller.edu/?page=engine&id=660


James V. Kohl
The Scent of Eros

[jvkohl]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17873857&ordinalpos=1&itool

=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel. Pubmed_RVDocSum

From the article:

"Recent

expression analysis shows that OR7D4 is selectively expressed in human nasal epithelium." Citation: Zhang, X. et al.

Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarray. Genome Biol.

8, R86 (2007).

Once again, there appears to be no support for the concept that human pheromones act through

what appears to be a non-existent human VNO.

James V. Kohl
The Scent of Eros

[Lokua]

so...like what...if i have a cold

ill be immune to phero's?

[BGuy20]

IIRC, I read that the receptor

forms differently in different people (same DNA but different end result... polymorphic or something), which they

said is why some people perceieve the smell of -None differently. I think the same article said that up to about

half of people can be "trained" to smell the scent after a while.

I've certainly noticed this happening with

me, I can notice -None much more easily than I could when I first started.

[jvkohl]

IIRC, I read

that the receptor forms differently in different people (same DNA but different end result... polymorphic or

something), which they said is why some people perceieve the smell of -None differently. I think the same article

said that up to about half of people can be "trained" to smell the scent after a while.

I've certainly

noticed this happening with me, I can notice -None much more easily than I could when I first

started.

Theoretically, exposure induces change in receptor expression via gene activation. The

theory behind this is very difficult to grasp without some knowledge of the immune system (e.g., genetics), and its

interaction with the neuroendocrine system. So most people might better understand the reductionist approach: the

immune and olfactory systems function in similar ways to recognize what is like us, or is not like us. We can

recognize a pig's smell as being like some of us, but hopefully not you or me. I am (half jokingly) concerned that

you might be slowly learning that you may smell like a pig. But even pigs don't require a VNO to "know" one pig

from another.

James V. Kohl
The Scent of Eros

[tenaciousBLADE]

hehe.. cute joke

there.
ummm...
I think this: "Theoretically, exposure induces change in receptor expression via gene activation."

is cool :cool::D
Animals and humans... what complex and cool beings.. :p

[jvkohl]

hehe..

cute joke there.

Happy to learn you "got" the joke. If I can't have some fun with this stuff once in a

while, I'll quit learning about it.

James V. Kohl
The Scent of Eros