View Full Version : Androgel?
Todd Spango
11-24-2006, 08:03 AM
Hello all.
I've been
reading the board for a few weeks now and have used the search feature extensively. Thus far I've been unable to
find the answer to my question. So, now that I'm allowed to post, I'll ask it directly.
My friend was
prescribed Androgel for low Test. levels. Upon applying it his wife noticed that the smell really turned her on. I
was wondering what,
other than Testosterone, is in the gel to have that effect? Is it just the Test.? Is there a
product that can duplicate that effect?
Thanks for any help you can provide.
TS
Todd Spango
11-24-2006, 04:10 PM
26 views and no replies?
Bruce
11-24-2006, 04:38 PM
Never heard of it, but it sounds
like a prescription drug, no?
B
Todd Spango
11-24-2006, 05:15 PM
Yes, it's a transdermal
Testosterone gel available by prescription only.
It was his(my friend's) wife's reaction to it, as well as my
wife's commenting on it, that led me to think there was something to this "Pheromone thing".
I've seen
Androgel mentioned on this forum, but no mention of it's pheromone-like properties.
I was hoping that someone
here would know about it.
Thanks,
TS
jvkohl
11-24-2006, 06:38 PM
I've seen
Androgel mentioned on this forum, but no mention of it's pheromone-like properties.
The only
associated smell is rather medicinal, most likely due to its 67% ethanol inactive ingredient. A preliminary study
with a very small number of men showed increased testosterone when smelling an ethanol control. Since an increase in
luteinizing hormone typically preceeds an increase in testosterone, either in men or in women, she might be
responding positively to the ethanol--in a manner similar to the effect of androstenol on luteinizing hormone (and
associated affect on mood.)
The testosterone content, in and of itself, is unlikely to have a pheromonal
affect--as so far as is currently known the most likely suspected human pheromones are metabolites of testosterone.
JVK
Todd Spango
11-24-2006, 06:56 PM
JVK,
Thanks for the
reply.
Would Androstenol be the pheromone most likely to reproduce the effect? or are there other variables?
jvkohl
11-24-2006, 07:43 PM
JVK,
Thanks
for the reply.
Would Androstenol be the pheromone most likely to reproduce the
effect?
Yes.
QUOTE=Todd Spango] or are there other variables?[/QUOTE]
The most notable
variables include menstrual cycle phase in women, but also the likely hormone effect to behavioral affect link,
which includes many more variables. Simply put, once the luteinizing hormone (LH) response is conditioned to
androstenol, any other associated odor or other sensory stimulus from the social environment can evoke the same
response. For example the association with androstenol evoked change in LH indicates that the odor (perceived or
not) of androsterone could elicit positive behavioral affects on women--especially during their ovulatory phase of
the cycle.
This does not however mean that an odor (perceived or not) must be associated with the response.
It could well be that visual stimuli could have the same behavioral affect--once the visual response has been
conditioned by olfactory/pheromonal input. This is detailed in my forthcoming review, which is laden with
neuroscientific jargon. Hopefully, some science journalist will take advantage of the opportunity to translate the
details into something more people can understand.
Based on a recent presentation, where audience members
did grasp the concept, I'm getting closer to a better understanding by all. But current non-"Scent of Eros" product
marketing continues to obscure the facts.
JVK
Todd Spango
11-24-2006, 08:00 PM
I think I understand what
you're saying. Sounds like a variant of Pavlov's Dogs. Condition/response?
maxo-texas
11-26-2006, 02:12 PM
Androgel is a testosterone
supplement gel.
It's by prescription.
It's very possible that the woman can smell the testosterone amid the
alchohol or after it drys.
jvkohl
11-26-2006, 06:38 PM
It's very
possible that the woman can smell the testosterone amid the alchohol or after it drys.
I've seen
nothing in the literature about either an effect of smelling testosterone on hormones or an affect on behavior. Do
you know of any hypothesis that suggests such a possibility?
JVK
maxo-texas
11-26-2006, 11:35 PM
Other than this data point
no.
But androgel is teste and alcohol.
If the lady is clearly aroused by it then either it's some random
placebo affect, some odd reaction to alcohol (which could be tested by applying alcohol without testosterone) or, by
simple reduction, it's the testosterone.
We know men can't smell none. I know of my 4 current girlfriends that
3 react weakly to mones (except all talky/relaxed under SOE) but one has reacted strongly.
I don't find it
implausible that some percentage of the female population would react to men with high testosterone
levels.
---
I'm discounting testosterone byproducts since she is apparently reacting to it clearly when it is
fresh rather than hours later.
jvkohl
11-27-2006, 07:07 AM
If the lady
is clearly aroused by it then either it's some random placebo affect, some odd reaction to alcohol (which could be
tested by applying alcohol without testosterone) or, by simple reduction, it's the
testosterone.
Data support the most likely conclusion: it's the alcohol, which acts in a manner
similar to pheromones (e.g., by effects on hormones, especially LH: luteinizing hormone.) I've cited the most
pertinent study below, and included my notes. There have been several other studies that address the hormone effect
and behavioral affects.
Meyer, Roger E. (1990) Ethanol beverage anticipation: Effects on plasma testosterone
and luteinizing hormone levelsA pilot study. Journals of Studies on Alcohol, 51, 4, 350-355.
My notes:
SNIFFING ALCOHOL INCREASES LH. ALCOHOL CAUSES UNCONDITIONED POSITIVE RESPONSE THAT IS REINFORCING. CHRONIC
CONSUMPTION REDUCES LH AND GnRH COMPARED TO TESTOSTERONE. REINFORCEMENT OF BEHAVIOR THROUGH ENVIRONMENTAL STIMULI
CAUSES INCENTIVE DRUG EFFECT.
I don't find it implausible that some percentage of the
female population would react to men with high testosterone levels.
There must be a biological
pathway that enables the reaction, and so far as is known, the biological pathway involves metabolites/byproducts of
testosterone--not testosterone itself.
I'm discounting testosterone byproducts since
she is apparently reacting to it clearly when it is fresh rather than hours later.
When it is
initially applied, it is the evaporation of the alcohol carrier that is associated with olfactory
appeal.
JVK
maxo-texas
11-27-2006, 12:06 PM
So then, he could test by
finding some alchohol and putting it on his skin and seeing how she reacted. Be a heck of a lot cheaper than
androgel.
However, that study certainly makes it a lot more probably it's the alcohol. I was unaware that
alcohol affected LH. So the smell of alcohol in a bar is having an affect on the hormonal balance of the women even
if they are not drinking.
jvkohl
11-27-2006, 09:40 PM
I was unaware
that alcohol affected LH.
Most people are unaware that pheromones effect LH, despite the fact that
this effect is well-known in mammals.
So the smell of alcohol in a bar is having an affect
on the hormonal balance of the women even if they are not drinking.
The term "effect" is typically
used in reference to a cause and effect relationship (e.g., pheromones effect hormones).
The term "affect"
is typically used in reference to behavior (e.g., pheromones affect behavior--usually behavior associated with
emotions.)
Technically speaking, to make a point: ethanol, whether or not its smell is consciously perceived
can be expected to have both an effect on hormones, and an affect on behavior. Better understanding of chemical
effects and affects will lead to better understanding of how the effects and affects of chemicals like androstenol
compare to the effects and affects of other chemicals found in their "alcohol" form.
However, the question
of whether the smell of alcohol in a bar is having an effect on the hormonal balance of the women even if they are
not drinking remains unstudied--so far as I know.
Perhaps a study could be inspired here by informing Forum
members that "brewer's yeast" (as used to make alcohol) contains a peptide hormone so similar to mammalian
gonadotropin releasing hormone (GnRH), that it activates LH in cultures of rodent (i.e., mammalian) pituitary cells.
Could the alpha mating pheromone of "brewer's yeast" (i.e., GnRH) be the reason for the effect of ethanol on human
levels of LH?
More details about this cross-species conservation of chemical signalling will be found in my
forthcoming article: The Mind's Eyes: Human Pheromones, Neuroscience, and Male Sexual Preferences. Journal of
Psychology & Human Sexuality.Volume: 18 Issue: 4 Cover Date: 2006. Page Range: 313 - 369. Simultaneously published
in the Handbook of the Evolution of Human Sexuality.
Abstract:
The across-species genetic
conservation of intercellular and extracellular chemical communication enables unicellular and multicellular
organisms to functionally distinguish between self and non-self. Non-self olfactory/pheromonal input from the social
environment elicits a vertebrate neuroendocrine response. The organization and activation of this neuroendocrine
response modulates the concurrent maturation of the mammalian neuroendocrine system, the reproductive system, and
the central nervous system during the development of sexual preferences that may be expressed in sexual behavior.
Psychophysiological mechanisms for the development of these sexual preferences include focus on unconscious affects
that are detailed in reciprocal cause and effect relationships. Olfactory/pheromonal conditioning elicits
neuroendocrine effects accompanied by unconscious affects on the development of sexual preferences. Integrating
these unconscious affects extends to humans a developmental model of behavior that includes the development of male
sexual preferences for other males.
I was unaware that alcohol affected LH.
Increased awareness can be beneficial, and overwhelming.
JVK
maxo-texas
11-28-2006, 09:31 AM
One theory could be that
drunk females reproduce more. So that would accentuate the initial effect over time causing their descendants to be
more common in the population.
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