jvkohl
01-13-2006, 06:59 PM
The Pheromone Androstenol
(5-androst-16-en-3-ol) Is A Neurosteroid Positive Modulator of GABAA
Receptor
http://jpet.aspetjournals.org/cgi/content/abstract/jpet.105.098319v1?ct
From my
1996 article....noradrenergic, dopaminergic, serotoninergic, and opiotergic pathways; inhibitory neurotransmitters
(e.g., gammaaminobutyric acid) and excitatory amino acids (e.g., glutamic and aspartic acids); and other brain
peptides including pineal secretions (melatonin) and corticotrophin releasing hormone, and the complex interactions
among them are subtle but functional species specific influences on the electrochemical transmission of neuronal
signals that the hypothalamus translates to the chemical signal GnRH (Grumbach & Styne, 1992).
Technical, of
course, but what all this means is that we're now closer to determinining how pheromones elicit changes in behavior
--like those changes elicited by psychotropic drugs that influence the pathways mentioned
above.
JVK
(5-androst-16-en-3-ol) Is A Neurosteroid Positive Modulator of GABAA
Receptor
http://jpet.aspetjournals.org/cgi/content/abstract/jpet.105.098319v1?ct
From my
1996 article....noradrenergic, dopaminergic, serotoninergic, and opiotergic pathways; inhibitory neurotransmitters
(e.g., gammaaminobutyric acid) and excitatory amino acids (e.g., glutamic and aspartic acids); and other brain
peptides including pineal secretions (melatonin) and corticotrophin releasing hormone, and the complex interactions
among them are subtle but functional species specific influences on the electrochemical transmission of neuronal
signals that the hypothalamus translates to the chemical signal GnRH (Grumbach & Styne, 1992).
Technical, of
course, but what all this means is that we're now closer to determinining how pheromones elicit changes in behavior
--like those changes elicited by psychotropic drugs that influence the pathways mentioned
above.
JVK