jvkohl
11-21-2005, 11:09 PM
I've repeatedly taken a
"who cares" approach to debate about the human VNO. Two new articles address the facts (although they use different
terminology for the biological core of mammalian reproductive sexual behavior): GnRH/LHRH, which is directly
affected by pheromonal input, and results in a change in luteinizing hormone levels.
Yoon H, Enquist LW,
Dulac C.
Olfactory Inputs to Hypothalamic Neurons Controlling Reproduction and
Fertility.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1629
0037&query_hl=3
"... in contrast to established notions on the nature of LHRH neuronal inputs, our
data identify major olfactory projection pathways originating from a discrete population of olfactory sensory
neurons but fail to document any synaptic connectivity with the vomeronasal system."
Boehm U, Zou Z, Buck
LB.
Feedback Loops Link Odor and Pheromone Signaling with Reproduction. Cell. 2005
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16290036&q
uery_hl=3
"...these experiments indicate that GnRH neurons receive pheromone signals from both odor and
pheromone relays in the brain and may also receive common odor
signals."
JVK
"who cares" approach to debate about the human VNO. Two new articles address the facts (although they use different
terminology for the biological core of mammalian reproductive sexual behavior): GnRH/LHRH, which is directly
affected by pheromonal input, and results in a change in luteinizing hormone levels.
Yoon H, Enquist LW,
Dulac C.
Olfactory Inputs to Hypothalamic Neurons Controlling Reproduction and
Fertility.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1629
0037&query_hl=3
"... in contrast to established notions on the nature of LHRH neuronal inputs, our
data identify major olfactory projection pathways originating from a discrete population of olfactory sensory
neurons but fail to document any synaptic connectivity with the vomeronasal system."
Boehm U, Zou Z, Buck
LB.
Feedback Loops Link Odor and Pheromone Signaling with Reproduction. Cell. 2005
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16290036&q
uery_hl=3
"...these experiments indicate that GnRH neurons receive pheromone signals from both odor and
pheromone relays in the brain and may also receive common odor
signals."
JVK