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DAdams91982
10-16-2004, 07:15 AM
This

is something that has been floating around the bodybuilding community for awhile (Cause we love new drugs to enhance

life :rofl: ) ... some definately worth a try.

And the Sex Super

Drug.... Cabergoline.


Sex and

Cabergoline


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By David Jay Brown

Cabergoline is a fairly new pharmaceutical that has enormous

potential to aid male stamina. Perhaps the most remarkable aspect of carbergoline is that it has been found to

substantially raise a man’s chances of sustaining multiple orgasms during sex. Some men on cabergoline are able to

have numerous multiple orgasms in rapid succession.

Cabergoline, which is marketed under the trade name of

Dostinex, is used to treat Parkinson's disease, to prevent women producing milk when they want to stop breast

feeding, and to lower prolactin levels in patients with a pituitary tumor. It is also sometimes used to help men

with sexual dysfunction.

It is cabergoline’s capacity to lower prolactin levels that makes it such a sexual

wonder drug for men. Prolactin is a single-chain protein hormone, closely related to growth hormone, that stimulates

the secretion of milk of women. The hormone also has the effect of reducing a man’s desire for more sex by

preventing new erections. Cabergoline has been found to to minimize the effects of the hormone prolactin, which is

produced by men at the point of orgasm. As a result, some subjects who tried the drug found that they were able to

have multiple orgasms in rapid succession.

In one study, 60 subjects, all healthy males, between the ages of 22

and 31, normally needed a break of 19 minutes between lovemaking sessions. However, after taking Cabergoline, they

were able to have several orgasms within a few minutes. Medical psychologist Manfred Schedlowski, who was involved

in the trials at Essen in Germany, said the drug raised the libido to enable the male to orgasm again more

quickly.

Schedlowski said, "We saw that prolactin rises after

orgasm and then thought maybe prolactin is a negative feedback system. Subjects who took this drug had decreased

prolactin levels, and reported their orgasm was better and there was a shorter refractory period. We interviewed

these subjects and found they were able to have multiple orgasms in very rapid succession. This is sitting very

nicely with our hypothesis that orgasms and sexual drive are steered by prolactin and dopamine in the

brain."

Cabergoline was reported to have no side effects on men during the tests, according to a paper that was

published in the International Journal of Impotence Research.

Researchers are carrying out trials to investigate

whether Cabergoline will have similar effects on women. Some anecdotal reports suggest that the drug has the

potential to enhance the intensity of orgasms in both men and women.


You can find more at

www.love-drugs.com/cabergoline.html (http://www.love-drugs.com/cabergoline.html)


Adams

Icehawk
10-17-2004, 04:58 PM
However, there may be a drawback. There’s evidence that the release of prolactin

in the brain, which surges during orgasm, promotes the growth of new neurons in the brain--a process called

neurogenesis. Researchers at the University of Cal-gary discovered that the release of prolactin spurs the

growth of new brain cells in the front regions of the brain involved in smell. So Cabergoline may allow men to

have multiple orgasms at the expense of
less brain growth. Sounds like a tough call to me.

Icehawk
10-17-2004, 05:04 PM
still every now and then? why

not?

CollegeStudent
10-17-2004, 06:32 PM
Hmm.. So "takin' care of

business" on a regular basis can make you smarter? Or just increase your sense of smell?

Icehawk
10-17-2004, 08:50 PM
Well not really, sure, but this

drug wont.... does this help??

DAdams91982
10-17-2004, 10:11 PM
However, there may be a drawback. There’s evidence that the release of prolactin in the brain,

which surges during orgasm, promotes the growth of new neurons in the brain--a process called neurogenesis.

Researchers at the University of Cal-gary discovered that the release of prolactin spurs the growth of new brain

cells in the front regions of the brain involved in smell. So Cabergoline may allow men to have multiple orgasms at

the expense of
less brain growth. Sounds like a tough call to me.
That must have been

left out of the part I copied... I just found that same article.. with that addition... Eitherway... 3 or 4 orgasms

in a row... or some new neurons for smell??... I dont think that is a tough choice. :rofl:

Adams

surfs_up
10-18-2004, 12:28 PM
Dostinex isn't a trivial medication that you can pop like a Viagra, and that isn't a trivial medication either.

Cabergoline is an ergot alkaloid derivative (so is LSD, as is Hydergeine, a cognitive enhancer) that will affect

more than one system, such as lowering blood pressure. Ergot derivatives have a reputation for being unpredictable.

Dostinex binds tightly to the dopamine receptors resulting in a pharmacologic effect that lasts approx. one week.

Right ? Be prepared for the full range of side effects for the next five days, minimum. Are you aware of your

baseline prolactin levels before experimenting with this ? There is a prolactin blood test. One theory had it that

as men aged their prolactin levels went up, causing them to develop old man boobies and deposits of body fat. Durk

Pearson and Sandy Shaw advocated taking anther prolactin inhibitor, bromocriptine (Parlodel), for reasons noone

seems interested in discussing, the Parlodel topic vanished. Durk and Sandy were looking a tad weird in the last

photos I saw, as in not the models of good hormonal regulation.

DAdams91982
10-18-2004, 11:09 PM
Dostinex

isn't a trivial medication that you can pop like a Viagra, and that isn't a trivial medication either. Cabergoline

is an ergot alkaloid derivative (so is LSD, as is Hydergeine, a cognitive enhancer) that will affect more than one

system, such as lowering blood pressure. Ergot derivatives have a reputation for being unpredictable. Dostinex binds

tightly to the dopamine receptors resulting in a pharmacologic effect that lasts approx. one week. Right ? Be

prepared for the full range of side effects for the next five days, minimum. Are you aware of your baseline

prolactin levels before experimenting with this ? There is a prolactin blood test. One theory had it that as men

aged their prolactin levels went up, causing them to develop old man boobies and deposits of body fat. Durk Pearson

and Sandy Shaw advocated taking anther prolactin inhibitor, bromocriptine (Parlodel), for reasons noone seems

interested in discussing, the Parlodel topic vanished. Durk and Sandy were looking a tad weird in the last photos I

saw, as in not the models of good hormonal regulation.
Please share some of the sides... cause the

numberous med. pubs I looked at... shared none... except maybe a little nausea.

Adams

surfs_up
10-19-2004, 07:16 AM
One website

listed these:

other possible effects are vasospasm (other ergot analogs are powerful vasoconstrictors, used

in modern medicine for migraine headache, in the bad old days, entire limbs would become gangrenous, that was from

the rye smut fungus that produced "ergotism") and thickening of the lung wall, althought that is a lot more likely

with chronic dosing..

I'd be cautious about using this medicine with any other known vasoconstrictor, as

over the counter decongestants are, or going to the dentist within ONE WEEK (remember, long washout time) and having

a nerve block with epinephrine. Epi and Dostinex could be a nasty mix, you'll know if your fingers start to turn

blue.

There's a paradox here, because it also is know for causing HYPOtension, or lower blood pressure,

sometimes these medicines can "flip" when combined with the wrong something else. I would not use it with any other

potentially blood pressure modifying drug, including Viagra, nor would I drink alcohol. You could either have a

vasospasm episode or a low blood pressure episode. On ocassion there is the possibility of circulatory collapse,

this actually happened to a friend of mine w/o warning, sort of spontaneously going into shock when the arterioles

suddenly relax.

If you want to play with Dostinex, don't consider combining it with any other recreational

drug, mind medicine (prozac, etc), and many OTC medicines for one week after administration.

Side

effects


Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal

pain


Indigestion (dyspepsia)


Low blood pressure (hypotension)


False perceptions of

things that are not really there (hallucinations)


Excessive fluid retention in the body tissues,

resulting in swelling (oedema)


Confusion


Dizziness


Nausea and

vomiting


Difficulty performing voluntary movements, resulting in jerky or involuntary movements or muscle

twitches (dyskinesia)


How can this medicine affect other medicines?

Care should be taken when

cabergoline is combined with the following medicines:
dopamine antagonists - phenothiazines (eg chlorpromazine),

metoclopramide, butyrophenones (eg haloperidol) and
macrolide antibiotics such as erythromycin.

DAdams91982
10-19-2004, 08:07 AM
Hahaha.. Damn man... I said

some... I couldnt find any of what you just supplied though... Then again... it wouldnt change my mind anyway... My

past is 10X worse than mixing this with alcohol. :drunk:

Adams

CollegeStudent
10-19-2004, 01:33 PM
Epi and

Dostinex could be a nasty mix, you'll know if your fingers start to turn blue.


Jez, why cant

nature make this easy? :)

Icehawk
10-19-2004, 03:08 PM
I still however believe that a

healthy non drugged up individual could experiment with this. Its not like I get every single side-effect of Vitamin

C when I take it?...

DAdams91982
10-19-2004, 10:27 PM
I still

however believe that a healthy non drugged up individual could experiment with this. Its not like I get every single

side-effect of Vitamin C when I take it?...
Like I said... I dont get the side effects at all.. unless you

take a couple percosets, and you call tired, euphoria a side. :thumbsup:

Adams

sprayit
11-24-2004, 10:47 AM
Speaking out of personal

experience, I found cabergoline rather disappointing after reading all the hype (multiple orgasm potential, 24 hour

libido). Expensive stuff, and its an MAOI which means drug interactions can be dangerous such as with certain

antidepressants or even alternative herbal meds. Anyhow here's my objective lowdown. Fyi: I'm 24, very healthy,

non-alcoholic, sex manic. Brand used: “cabaser” (european brand of cabaser). Dosage taken:

0.5mg

Took about an hour to kick in. It did have a slight “drugged” feeling about it. Felt fine

and pleased with myself. I did notice an increased interest in sex, though nothing earth shattering, just a more

full feeling, “puffy” sensitive to pleasure penis – don't know the words – sort of like

you've been very horny for quite a while, but have stepped away from the sexual stimulus, with a fullness of the

penis and sexual interest still remaining. This is not like a viagra penis, which feels more like a stick in your

pants. Cabergoline works on your mind being a dopamine agonist, not your penis or plumbing anywhere else down

below.

Anyhow, sex itself was different in that I was able to last a lot longer than usual after penetration

commenced. A normal for me is between 10-20 minutes, though on cabergoline I felt as though I could avoid orgasm as

long as I wanted. It felt like it was always “just around the corner.” The sex did feel slightly more

satisfying as I could pump away at any pace I liked safe in the knowledge that it wouldn't end sooner than I

wanted. The orgasm was powerful too, I felt it “further inside”

After orgasm however, there was a

mild to moderate headache, and it did feel localised in the pituitary area (sort of between my temples in my head).

It lasted for about an hour, though waned off towards the end. I must have simply taken too much. Not

pleasant.

The slightly drugged feeling was gone after about 12 hours, but the sexual effects from the drug

remained for three days following, with effect lessening on each day.

Experienced no nausea, though I would

recommend a lower dosage if you're in your twenties. The pills were tiny little things too, hard to split. All in

all, I prefer bromocriptine, you need to take a little more as it's less strong, but as its patent has long

expired, its about ¼ the price of its more expensive cousin.

Cabaser is much cheaper than dostinex, despite

being the same thing chemically. I think the price difference has something to do with the different range of

applications in the USA compared with Europe for cabergoline.

Overall, nothing amazing, but certainly

interesting stuff. Make sure you do your own research as I did before messing with it, don't take my word for it.

JasonLJS
11-24-2004, 12:44 PM
Interesting, that stuff is way

too expensive to experiment with without having more scientific evidence on the pros and, more importantly, the

cons. Will have to look into the "bromocriptine."

ismellgood
11-25-2004, 02:51 AM
sprayit,
Thanks for the

user report. Did anyone else try it?

Madeleine
12-05-2004, 01:20 AM
I was just wondering if anyone knows what side effects there are to mixing cabergoline (dostinex), with

cocaine?
Thanks!

Icehawk
12-05-2004, 04:25 PM
LOL how low key of you, but I

guess it would be nice to know....