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CptKipling
07-31-2004, 05:53 PM
http:/

/www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14630096 (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14630096) - Microbial

pathways leading to steroidal malodour in the axilla.

DrSmellThis
07-31-2004, 09:07 PM
Great post. This is the type

of knowledge that is potentially helpful for forum members!

jago25_99
04-26-2005, 11:47 AM
If bacteria are not present

does this:

- prevent `bad` body odour?
- prevent `good` body odour?



Odorous steroids,

specifically the 16-androstenes, 5alpha-androstenol and 5alpha-androstenone, are widely accepted as being

contributors to underarm odour
If the the bacteria is not involved in the good pheromones then we got a

way of concentrating natural `mones!

Oops! Here's the answer; there's bacteria that help and ones that

don't. So you need to make something that only kills some and that's waaay harder:



Jago:
I have

used that rock crystal thing when I was a little kid.

It may work good, but from what I have seen, having

some bacteria is good for you.

Now there is a type of bacteria that does convert pheromones and one that

doesn't:

"The metabolism of 16-androstenes was studied in vitro in the presence of two aerobic coryneform

bacteria, previously shown to metabolize testosterone as well as being capable of producing odour from extracts of

axillary sweat in an odour-generation test. Although both coryneforms caused complex metabolic reactions and were

capable of oxidation or reduction at C-3 and C-4, the overall direction favoured reduction. For example, large

quantities of the more odorous 5 alpha-androstenone and 3 alpha-androstenol were formed from androstadienol and

androstadienone. In contrast, strains of corynebacteria, unable to produce odour and incapable of metabolizing

testosterone, were also unable to metabolize 16-androstenes."

I think the bacteria that is unable to

metabolize testosterone cannot convert pheromones, but may be able to control the bacteria that will.

I'd

like to try and find out how to get a high ratio of the stuff that does not convert pheromones than the stuff tha

does in my personal chemistry, rather than trying to eliminate it all.

NaughtieGirl
04-26-2005, 12:02 PM
Great

post. This is the type of knowledge that is potentially helpful for forum members!
:lol: To get the full

effect of transformation to natural signature, I shall apply the synthetic pheromones to my axilla tonight! I'll

hand out gas masks as well!

Just having some fun, Capt - Thank you for the link!

CptKipling
04-26-2005, 03:35 PM
Their words, not mine!



...smart arse... ;)


Going back to the study, the chemicals that they mention are good possibilities for

additional pheromones:

"In summary, the formerly implicated 4,16-androstadien-3-one, 5alpha-androstenone and

5alpha-androstenol were detected, along with previously unreported hydroxy- and keto-substituted 16-androstenes,

16-androstatrienones and 16-androstatrienols. Additionally, many other metabolites with steroidal fragmentation

patterns were present, but have remained unidentified."

NaughtieGirl
04-26-2005, 04:05 PM
Their

words, not mine!

...smart arse... ;)


Going back to the study, the chemicals that they mention are good

possibilities for additional pheromones:

"In summary, the formerly implicated 4,16-androstadien-3-one,

5alpha-androstenone and 5alpha-androstenol were detected, along with previously unreported hydroxy- and

keto-substituted 16-androstenes, 16-androstatrienones and 16-androstatrienols. Additionally, many other metabolites

with steroidal fragmentation patterns were present, but have remained unidentified."
That makes sense. To

save me alot of time researching, would you know off the top of your head whether any of these are already being

synthesized and if so, what name they were given? Or are we possibly looking at the next generationof pheromones?



Euh... you meant "smartie tush" right?

thr3shold
04-26-2005, 07:36 PM
so let me get this straight,

'bacterial action' doesn't refer to e.coli getting it on?

CptKipling
04-27-2005, 07:59 AM
so let me get

this straight, 'bacterial action' doesn't refer to e.coli getting it on?
Erm no, there is more than one

type of bacteria around. We are talking about corynebacteria in this instance.


Naughtie,

Those other

pheromones aren't disclosed as ingredients in any product that I know of, but you can buy them from a chemical

manufacturer.

And yes, I think that was an accurate translation.

Rbt
04-27-2005, 04:08 PM
Euh... you

meant "smartie tush" right?
Mensa Butt?
:lol: