Interesting Research on PT-141

[SwingerMD]

Hi

Everyone,

I just came across this interesting article on cnn.com:

http://www.cnn.com/2004/HEALTH/06/29/rat

.aphrodisiac.reut/index.html (http://www.cnn.com/2004/HEALTH/06/29/rat.aphrodisiac.reut/index.html) .
It would be really awesome if there was a pheremone product that would work on

the same pathway that PT-141 does. I'm going to see if there are any scientific papers on the

subject.
____________________

-SwingerMD

[Bruce]

Wow! Interesting article. Now if we

can get that in cologne format. :-)

B

[belgareth]

It was on Yahoo news too. The

only thing I didn't like is that it would be injected or as a nasal spray. Here's the one I

saw.
[url="http://story.news.yahoo.com/news?tmpl=story&cid=573&ncid=757&e=3&u=/nm/20040629/od_nm/health_aphrodisiac

_dc"]http://story.news.yahoo.com/news?tmpl=story&cid=573&ncid=757&e=3&u=/nm/20040629/od_nm/health_aphrodisiac_dc[/ur

l]

If you find a good technical article, I'd like to read it.

[dping28]

Ok Bruce you need to get that

stuff :D Try dissolving it in one of the products and see what happens ;)

[DAdams91982]

Hahah.. But wene was the

last time you talked a female into shoving something in their nose to get horny for you???? :LOL: ..........

Previous cocaine users... need not respond. hehe

A1C Adams

[Bruce]

If it works as a nasal spray, there

must be some potential there.

Bruce

[SwingerMD]

Bel,

Yeah the nasal spray

would imply that we'd have to have this stuff in high concentrations if we were to put this stuff on in cologne

form. At least we know that it can act on the body via the nose.

Oh and here's the company's website:

http://www.palatin.com/html/products/pt_141.aspx
____

________________
-SwingerMD

[belgareth]

Swnger,

Thanks!

[DAdams91982]

Is there anyway to actually

get this yet... or is it still in its infant state???


A1C Adams

[SwingerMD]

Bel,

Found an article

published in Annals of the New York Academy of Science:

http://www.annalsnyas.org/cgi/content/abstract/994/1/

96 (http://www.annalsnyas.org/cgi/content/abstract/994/1/96)
Tell me if you can't see the full text version.
_____________________
-SwingerMD

[belgareth]

Swinger

No, I can't see

the full text of it. Can you post or PM it?

[BDC_Concepts]

Bel,



Yeah the nasal spray would imply that we'd have to have this stuff in high concentrations if we were to put

this stuff on in cologne form. At least we know that it can act on the body via the nose.

Oh and here's the

company's website:

http://www.palatin.com/html/products/pt_141.aspx




-SwingerMD

The nasal spray is intended to get the active ingredient into the

blood stream quickly, which is does quite efficiently. Simply smelling the product would likely not induce the same

result as it clearly needs to enter the bloodstream (i.e. - injection into rats). However, as Bruce mentioned, a

true nasal spray might be a possibility.......NEXT STEP, Trying to get a female to sniff it! :D

heheheh
____________________

[einstein]

Hmmm, maybe a transdermal

solution you could "accidentally" spill on the target. Make it smell and feel like a cocktail, blend in perfectly

at bars. About as ethical as roofies.

[DrSmellThis]

PT-141 is a melanocortin

agonist, and a 100x more powerful synthetic version of alpha-MSH; a skin pigmentator dervived from ACTH, the adredal

stimulating hormone produced in the pituitary. The drug works on a neurological rather than vascular level.

[DrSmellThis]

They're calling it the

"Barbie drug", as it makes you tan and lose weight, too. :D

[belgareth]

They're

calling it the "Barbie drug", as it makes you tan and lose weight, too. :D
Wonderful! Since losing my

thyroid many years ago, I do not tan. There's an Australian company called Epitan doing some research on that

subject. But something to increase libido and tan all at the same time. It doesn't get much better than that.



Swinger,

Thanks. I'll get some time in the morning and read it.

Bel

[SwingerMD]

The drug works on a

neurological rather than vascular level.
Thanks Doc. I saw this too. That's why I'm wondering if this

stuff is working on the same pathways as mones rather than working on the bloodstream

(vascular).
_____________________
-SwingerMD

[Bruce]

Good stuff, guys.

Great

thread!
B

[dping28]

All these positives, Im afraid to

ask what the negative side effects are.

[burgerama1960]

do shots of this stuff

[Friendly1]

All these

positives, Im afraid to ask what the negative side effects are.
Probably about five-to-ten years after it

is classified as a date rape drug. If it really works, and if people can find ways to slip it to unsuspecting

women, they will do it.

[SwingerMD]

Bel,

It took me quite a

while, but I finally found this paper with the info of the effects of PT-141 on female rats :

http://www.pnas.org/cgi/search?fulltext=PT-141&submit.x=9&submit.y=10

I can't seem to get a clean

download at home so hopefully I can download and view at work.


____________________
-SwingerMD

[happyman]

Yes. Good articles. If you could

get it into cologne it would be, well....interesting. Maybe you would get mounted by a human female. Only thing is

we do not have any idea if it has any effect what-so-ever on humans. Hopefully time will tell.
Read the Yahoo

article. And now one last note:
How the hell does a Rat "flirt".....??? lol


happy

[SwingerMD]

Happy,

There have been

several publications that I have found on the effect of PT-141 on male sexual disfunction. As for human female

research:

Phase 1B Study - Females: PT-141 was administered to premenopausal women without sexual

dysfunction and was shown to be safe and well tolerated. A secondary endpoint in this study was to assess PT-141's

affect on vaginal blood flow. Results showed a significant difference in the increase in vaginal blood flow in

subjects treated with PT-141 versus placebo.
Found this here:

http://www.palatin.com/html/products/pt_141_development_status.aspx
I can't find a paper to go

with this clinical trial yet.

In upcoming research they plan to conduct a Phase 2 study of female patients

with sexual arousal disorder.
____________________
-SwingerMD

[OmnipotentOne]

I bought a huge number of

shares of PTN stock last year for $1.45 per share. I hope it does the "Viagra" thing and sends the stock through the

roof after the trials are complete.

As it stands right now, every time there is press release the stock

spikes pretty good. The clinical trials results have been amazing.

[bjf]

Omni, why not sell it right now?

You'll have tripled your investment...

[Bruce]

Omni, why not sell it

right now? You'll have tripled your investment...

It's tripled? Where do I get some of this? (the

stock)

So, when they finish the tests and it gets approved, what is it going to be used for? Like Viagra for

ladies? Sort of "hey Doc, my libido is shot" and then he writes the prescription for this stuff?

You know,

guys have been dreaming about a "spanish fly" type drug since the beginning of time. I guess this is finally it,

but it seems like the potential for this being used as a "date rape" drug is high. Come to think of it, I wonder if

women ever sneak Viagra into their husbands food? It would be easy to do, wouldn't it?

B

[OmnipotentOne]

Hi Bruce, how are you

doing? Give me a call next time your in Vegas.

The stock, (PTN) is traded on the American exchange, it's a

listed stock so it can be purchased through any brokerage (online or brick & mortar).

The product was

developed for men originally, but the trials were so good that in "Phase 2" they were given permission to test on

women also (which has produced equally dramatic results), that's why there is so much publicity on 141 and women

recently, but it is designed for men as not just an erectile dysfunction remedy, but a libido enhancer also (which

would be the first true aphrodisiac ever produced).

As to those that ask why I don't sell the stock? I

believe it will go well over 25 in a couple of years, with a good chance of a stock split (based on the number of

shares that were initially offered in the IPO, reported insider purchases, and probable demand for shares upon USDA

approval). At least that's my belief and opinion.

[bjf]

Omni, what if it just fizzles out?

[belgareth]

That's a risk you take when

you play the market. It sounds like a pertty good bet though.

[OmnipotentOne]

I put "USDA" in my previous

post by mistake, It should be "FDA". Sorry about that.

[kossBass]

hehe dude use the EDIT button

right under your post where it says Quote and right beside it, it says EDIT :D

[OmnipotentOne]

I would have, but the

people that already read my post are unlikely to go back and re-read it to see if it has been edited, so I corrected

my mistake for all to see through a new post.

[kossBass]

oh hehe smart smart :D

[Whitehall]

As we've discussed at length in

earlier threads, females need control of their sexuality. They usually do so unconsciously by internal regulation

of their libido - they have internal processes that enhance their libido and processes that inhibit it. These

evolved to protect women and ensure that they pass their genes on to worthy men.

With our men's pheromones,

we stimulate the female libido but as we well know, inhibitions remain and we seldom get in a woman's panties

immediately. Ultimately, we men need to be worthy of a woman's charms but it's OK to nudge her threshold in our

own direction a tab.

With PT-141, we've found another external way of stimulating libido. To get a woman to

try it we have to be honest about it but puffery is still allowed!

If I had a bottle of the nasal spray, I

would offer to share it with a woman who was interested in sex if not completely decided on putting out for me.

I'd describe it as part of a natural compound that increases affection and warm feelings on both of our

parts.

What woman isn't proud of being affectionate and warm? (Extra points for those who answered

"Hiliary.") By mentioning affects on both genders, it levels the playing fields.

As to the tanning, does that

mean we should have sex in a tanning booth?